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Narcolepsy
Narcolepsy
is one of the most misunderstood of all sleep disorders.
In simple terms, narcolepsy is a breakdown of normal
boundary control of Rapid Eye Movement (REM) sleep. REM
sleep is loosely known as dream sleep. Normal adults go
through brainwave cycles every ninety minutes while
asleep. REM sleep occurs at the end of each nightly
sleep cycle but normal people would not have REM sleep
during daytime naps. Narcoleptic patients often fall
asleep during the daytime and will have REM sleep during
these naps.
Normal
REM sleep involves paralysis of the body, so that one
does not act out their dreams. This paralysis occurs for
most of the muscles of the body but does not occur for
the muscles that control eye movements and the diaphragm
which is a trampoline like muscle dividing the abdomen
and the chest. The diaphragm contracts during
inspiration pulling down on the lungs, inflating them,
and thus allowing inspiration to occur. The diaphragm is
not paralyzed during REM so that breathing can continue
while one is dreaming.
Cataplexy is a symptom of narcolepsy. Cataplexy is the
loss of muscular control that may occur with strong
emotions, such as laughter, crying, or anger. This may
result in the knees buckling, an arm going weak, or even
weakness of the face. The weakness usually lasts for
several minutes but the person with narcolepsy
experiencing it is fully conscious during this time.
Cataplexy may seem like an odd symptom for a narcoleptic
to have, but it is really the paralysis that would
normally occur during nighttime REM sleep except that it
is occurring during the daytime. About forty to sixty
percent of patients with narcolepsy have cataplexy.
Sleep
paralysis is another symptom that may be seen in
narcolepsy. Sleep paralysis is also a symptom that about
half of the normal population will experience at least
once or twice during their lifetimes. Have you ever
awoken in the morning to know that you were awake but
you couldn’t move your body? This is sleep paralysis. It
is a blending of both wakefulness and REM sleep. The
brain knows that it is awake, but the part of the
brainstem that allows the paralysis to occur is still in
REM sleep. This is just another example of how
narcolepsy is a breakdown of REM sleep boundary control.
Patients with narcolepsy often have vivid daytime
dreams, although some patients will not remember them.
Some patients will go into a vivid dream directly from
wakefulness. This can be problematic if they happen to
be driving a car at the time.
Symptoms of narcolepsy can begin abruptly, and usually
begin in the teens or twenties but may occur at any age.
There is an increased risk of getting narcolepsy if
there is a positive family history for it. Much recent
research suggests that it is an autoimmune disorder,
like multiple sclerosis or rheumatoid arthritis.
You
should be checked for narcolepsy if:
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you
have severe daytime sleepiness, even after having
had a full night's sleep.
-
you
fall asleep when you do not intend to, such as while
having dinner, talking, driving, or working.
-
you
collapse suddenly or your neck muscles feel too weak
to hold up your head when you laugh or become angry
or surprised.
-
you
find yourself briefly unable to talk or move while
falling asleep or waking up.
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